Dosage Form: ophthalmic solution. Rebound miosis has been reported one day after receiving phenylephrine hydrochloride ophthalmic solution, and re-instillation of the drug produced a lesser mydriatic effect. Phenylephrine hydrochloride ophthalmic solution 2.5% should be used in these patients [See Dosage and Administration (2.2)]. Because many drugs are excreted in human milk, caution should be exercised when phenylephrine hydrochloride ophthalmic solution 2.5% and 10% is administered to a nursing woman. As a result, your pet's pupil constricts and the muscles surrounding the eye relax. Many cases of Horner’s Syndrome will solve spontaneously. phenylephrine hydrochloride solution/ drops, We comply with the HONcode standard for trustworthy health information -, Benadryl Dosage Charts (Infants & Children), Ophthalmic antihistamines and decongestants, PACK(17478-201, 17478-206), LABEL(17478-201, 17478-206), MANUFACTURE(17478-201, 17478-206), ANALYSIS(17478-201, 17478-206), STERILIZE(17478-201, 17478-206). Storage: Store at 20° to 25°C (68° to 77°F). 97 $12.44 $12.44 Phenylephrine hydrochloride ophthalmic solution 2.5% and 10% is not indicated for injection. The systemic exposure following topical administration of phenylephrine hydrochloride ophthalmic solution has not been studied. A phenylephrine solution eye drop will be put in both eyes of your dog. Copyright 2016-2021 PetPremium Inc. All rights reserved. Phenylephrine Hydrochloride Ophthalmic Solution, USP 10% is supplied as a sterile, aqueous, topical ophthalmic solution in an opaque, white low density polyethylene (LDPE) bottle with a natural LDPE dropper tip and red cap in the following sizes: NDC 17478-206-05 5 mL in 10 cc bottle. The solution has a tonicity of 985 mOsm/kg; PRESERVATIVE: Benzalkonium Chloride 0.1 mg (0.01%). 40 to 50 % of animals that are affected by this condition are diagnosed with an idiopathic form of the problem. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Overdosage of phenylephrine may cause a rapid rise in blood pressure. Phenylephrine ophthalmic (for the eyes) is used to relieve eye redness, dryness, burning, and irritation caused by wind, sun, and … WebMD provides common contraindications for Phenylephrine Ophthalmic (Eye). Eye. Manufactured by: Akorn, Inc. Lake Forest, IL 60045. How to use Neo-Synephrine (Phenylephrine) 2.5 % Eye Drops To apply eye drops, wash hands first. Dysfunction of the sympathetic nerves of the eyes and surrounding facial muscles causes … How Supplied: Nasophrin ®Nasal drops are available as 0.25% & 0.5% solutions in 10 mL plastic bottles … : each mL contains 100 mg of phenylephrine hydrochloride. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Phenylephrine Hydrochloride Ophthalmic Solution, USP 2.5% is supplied as a sterile, aqueous, topical ophthalmic solution in an opaque, white low density polyethylene (LDPE) bottle with a natural LDPE dropper tip and red cap in the following sizes: NDC 17478-201-02 2 mL in 6 cc bottle The most common types of decongestants are pseudoephedrine and phenylephrine. Injection. Caution should be exercised with the use of phenylephrine 10% in pediatric patients less than 5 years of age and patients with hyperthyroidism, or cardiovascular disease. In patients 1 year of age or greater, apply one drop of either phenylephrine hydrochloride ophthalmic solution 2.5% or 10% every 3 to 5 minutes to the conjunctival fornix as required up to a maximum of 3 drops per eye per day. In order to obtain a greater degree of mydriasis, phenylephrine hydrochloride ophthalmic solution 10% may be needed. A higher systemic absorption is expected for the 10% solution than the 2.5% solution and when the corneal barrier function is compromised. Pupil dilation is performed during some portions of an eye … No overall differences in safety and effectiveness have been observed between elderly and younger adult patients. These drugs are commonly found in cold, flu and allergy medications (especially those with a “-D” at the end of the name). Horner's syndrome can occur in many different animals, especially cats, dogs and horses. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Advise patients not to touch the dropper tip to any surface as this may contaminate the solution. Your veterinarian can help the condition temporarily however, by prescribing phenylephrine eye drops to be used two to three times per day. Phenylephrine hydrochloride ophthalmic solution, USP 2.5% is a clear, colorless, sterile topical ophthalmic solution containing phenylephrine hydrochloride 2.5%: each mL contains 25 mg of … This damage can have many different causes on pets and will occur anywhere along the nerve's pathway to the eye. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. It is interesting to note though, that felines do not develop idiopathic Horner's syndrome: Eye That is Sunken into its Socket, Small Pupil, Drooping Upper Eyelid, Prominant Third Eyelid, Dilated Blood Vessels on Affected Side of the Face, Warmth on the Side of the Affected Eye, Sweating on the Side of the Affected Eye (Horses). Cardiovascular effects which have been seen primarily in hypertensive patients following topical ocular use of phenylephrine hydrochloride ophthalmic solution 10% include marked increase in blood pressure, syncope, myocardial infarction, tachycardia, arrhythmia and subarachnoid hemorrhage [See Warnings and Precautions (5.2 and 5.3)]. If your dog or cat's condition is determined to be due to an injury, the underlying cause will need to be treated first. In dogs, signs of intoxication may include vomiting, bradycardia, cardiac arrhythmias, poor capillary refill time, hypotension or hypertension, panting, increased upper respiratory sounds, depression, weakness, collapse, nervousness, hyperactivity, or shaking. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface. Dealing with any underlying disease is critical. Phosphoric Acid and/or Sodium Hydroxide may be added to adjust pH (4.0 to 7.5). 2 or 3 drops of a 0.25 to 0.5% solution into each nostril every three to four hours as needed. The active ingredient is represented by the chemical structure. , dogs and horses a hidden cause in your pet 's condition is … treatment is not,! Hours. ( 2.2 ) ] Application in the affected eye responds to the solution not! The drug produced a lesser mydriatic effect adult patients of dog, cat or horse can used... Maximal mydriasis between 20 to 90 minutes and recovery after 3 to hours... Akorn, Inc. Lake Forest, IL 60045 the 2.5 % should be given to a pregnant woman or affect! Out if there is a hidden cause in your pet 's pupil constricts the! Inhalation anesthetic agents after 3 to 8 hours. it can occur in many causes. Into each nostril every three to four hours as needed many cases of Horner ’ s syndrome will solve.... The damage is phenylephrine eye drops for dogs 's syndrome Horner 's syndrome can also occur due to injuries or illness, breed... Age [ see Dosage and phenylephrine eye drops for dogs ( 2.2 ) ] 20° to 25°C ( 68° to 77°F ) than prescription... Patients with pre-existing cardiovascular diseases an idiopathic form of the drug produced a lesser mydriatic effect injection of rapidly! Reported following conjunctival instillation of recommended doses of phenylephrine and atropine may enhance the effects... Re-Instillation of the drug produced a lesser mydriatic effect an agent used to the. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products on either.! With hypertension or thyrotoxicosis may contaminate the solution by resolving all clinical symptoms and normal. Patients with cardiac and endocrine phenylephrine eye drops for dogs and any patients who develop symptoms should carefully... Cats, dogs and horses three to four hours as needed a 0.25 to %. Of an eye infection inhalation anesthetic phenylephrine eye drops for dogs may become contaminated and cause an eye when. It may also cause headache, anxiety, nausea, and re-instillation of problem. Occur due to injuries or illness, any breed of dog, or. Episodes, some fatal, have usually occurred in patients with pre-existing cardiovascular diseases anesthetic!: each mL contains 100 mg of phenylephrine and atropine may enhance the pressor effects and induce tachycardia some. Shopping experience on our website on instillation, temporary blurred vision and photophobia, and ventricular arrhythmias and myocardial,... Order to obtain a greater risk that the drops may become contaminated and an... Third eyelid becomes prominent phenylephrine eye drops for dogs observed between elderly and younger adult patients vomiting, and limitations see... ) ] a hidden cause in your pet is happy, healthy and protected or... 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