Tacrolimus works by lowering immune system activity to prevent the body from attacking a transplanted organ. This medication is an immunosuppressant, prescribed for preventing organ rejection during transplantation. Accidental oral ingestion of Tacrolimus ointment may lead to adverse effects associated with systemic administration of Tacrolimus. Tacrolimus ointment is the first in the new class of steroid-free Topical Immunomodulators (TIMs), and as such represents the first true breakthrough since the introduction of topical steroids more than 50 years ago for the treatment of T-cell mediated inflammatory skin diseases such as atopic dermatitis. Yes, tacrolimus is the active ingredient in Prograf. Tacrolimus ointment is not for oral use. Read Reviews (3) Find Lowest Prices. 40 Shahid Tajuddin Ahmed Sarani, Tejgaon I/A, Dhaka -1208, Bangladesh, © 2021. Tacrolimus Ointment in Special Treatment Indications. Tacrolimus is a topical ointment originally produced by Astellas Pharma under the brand name Protopic and approved by the U.S. Food and Drug Administration to treat atopic dermatitis, or eczema.Tacrolimus can also be used to treat morphea.. The safety of Tacrolimus ointment has not been established in patients with generalized erythroderma. tacrolimus topical. If experienced, these tend to have a Severe expression. Inadvertent switching between oral tacrolimus products has been associated with reports of toxicity and graft rejection. Tacrolimus ointment is indicated for short-term and intermittent long-term therapy in the treatment of patients with moderate to severe atopic dermatitis in whom the use of alternative, conventional therapies are deemed inadvisable because of potential risks, or in the treatment of patients who are not adequately responsive to or are intolerant of alternative, conventional therapies. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Benefits of topical tacrolimus are partially sustained for 2 weeks after termination of drug treatment, although there is a degree of clinical relapse in most cases. OTHER NAME(S): Tacrolimus Ointment. US Brand Name. Tacrolim 0.1% Ointment: Each tube contains 5 gm Tacrolimus ointment. Tacrolim Ointment is also indicated in other skin conditions such as chronic cutaneous graft-vs-host disease, hand and foot eczema, allergic contact dermatitis, psoriasis, lichen planus, facial lichen, vulvar lichen sclerosus, pyoderma gangrenosum, leg ulcers in rheumatoid arthritis, steroid-induced rosacea & alopecia areata, annular erythema, chronic actinic dermatitis and recalcitrant facial erythema. Tacrolimus ointment is a topical drug (a drug that is applied to the skin) that is used for the treatment of atopic dermatitis (). MEDICATION GUIDE PROTOPIC [pro-TOP-ik] (tacrolimus) Ointment 0.03% Ointment 0.1% Read the Medication Guide every time you or a family member gets PROTOPIC Ointment. Tacrolimus topical ointment should not be used by people with a suppressed immune system. Protopic; Descriptions. This leads to a general decrease in the entire inflammatory cascade. Generic Name: Tacrolimus 0.1% Ointment (ta KROE li mus) Brand Name: Protopic. The experience with Tacrolimus ointment when used by pregnant women is too limited to permit assessment of the safety of its use during pregnancy. Fanatic Pharmaceuticals Kanchanagar, Rewari Opposite R.D.S College, Silvassa Road College, Kanchanagar, Rewari - 123401, Dist. Peak tacrolimus blood concentrations ranged from undetectable to 20 ng/mL after single or multiple doses of 0.03% and 0.1% PROTOPIC Ointment, with 85% (75/88) of the patients having peak blood concentrations less than 2 ng/mL. It is used after allogeneic organ transplant to lower the risk of organ rejection, and also as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis. To ensure maintenance of therapeutic response when a patient is stabilised on a particular brand, oral tacrolimus products should be prescribed and dispensed by brand name only. Prograf is the brand name while tacrolimus is the generic name. Nursing Mothers: Although systemic absorption of Tacrolimus following topical applications of Tacrolimus ointment is minimal relative to systemic administration, it is known that Tacrolimus is excreted in human milk. Apply a thin layer of Tacrolim ointment onto the affected skin areas twice daily and rub in gently and completely. We are amongst the most reputed names in the industry, offering Tacrolimus Ointment. The oral form is used to suppress the immune system in people who have had an organ transplant. 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